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卢珺 博士

发布日期:2022-05-13    作者:广西糖尿病系统医学重点实验室     来源: 广西糖尿病系统医学重点实验室    

卢珺,女,1986年10月生,毕业于香港中文大学生物医学专业,哲学博士,副教授,硕士研究生导师。主要从事离子通道和心肌细胞病理生理学的研究,主持国家自然科学基金地区项目1项、广西自然科学基金面上项目1项、广西科技基地和人才专项1项、广西高校中青年教师科研基础能力提升项目1项。发表SCI检索论文17篇,其中以第一作者身份发表5篇SCI文章。

主持项目情况:

(1)离子通道PC2通过钙信号调控的自噬在心肌缺血/再灌注损伤中作用的研究(国家自然科学基金地区项目,82160064,主持在研)

(2)PKD2调控细胞钙水平对心肌缺血再灌注损伤中自噬的作用机制(广西自然科学基金面上项目,2018GXNSFAA281052,主持完成)

(3)Polycystin-2调控的自噬在心肌缺血再灌注损伤中的作用研究(广西科技基地和人才专项,桂科AD18281012,主持在研)

(4)PKD2介导自噬在心肌缺血再灌注损伤中的作用及机制研究(2019年度广西高校中青年教师科研基础能力提升项目,2019KY0531,主持完成)

主要SCI收论文:

(1)Jun Lu; Xin Ma; Wen-Cong Gao; Xin Zhang; Yuanling Fu; Qian Liu; Lixiang Tian; Xiao-Dan Qin; Weimin Yang; Hong-Yi Zheng; Chang-Bo Zheng; Gastrodin Exerts Cardioprotective Action via Inhibition of Insulin-Like Growth Factor Type 2/Insulin-Like Growth Factor Type 2 Receptor Expression in Cardiac Hypertrophy, ACS Omega, 2021, 6 (26): 16763-16774.(共同一作)

(2)Fuman Yan;Jun Lu; Yunting Zhang; Xiao Li; Wai-Ho Chan; Qiannan Zhao; Hiu-Yee Kwan; Haimei Liu; Xiaoqiang Yao; Resveratrol stimulates the Na+–Ca2+ exchanger on the plasma membrane to reduce cytosolic Ca2+ in rat aortic smooth muscle cells, Journal of Cardiovascular Pharmacology, 2020, 76(5): 610-616.(共同一作)

(3)Hongyan Wang;Jun Lu; Wen-Cong Gao; Xin Ma; Na Li; Zhituan Ding; Chunmei Wu; Maoceng Zhu; Guanrong Qiao; Chuang Xiao; Changhong Zhang; Chen Chen; Zhiying Weng; Weimin Yang; Chang-Bo Zheng; Donepezil down-regulates propionylation, 2-hydroxyisobutyrylation, butyrylation, succinylation, and crotonylation in the brain of bilateral common carotid artery occlusion-induced vascular dementia rats,Clinical and Experimental Pharmacology and Physiology, 2020, 47(10): 1731-1739.(共同一作)

(4)Jun Lu; Kenneth R. Boheler; Liwen Jiang; Camie W. Chan; Wan Wai Tse; Wendy Keung; Ellen Ny Poon; Ronald A. Li; Xiaoqiang Yao; Polycystin-2 Plays an Essential Role in Glucose Starvation-Induced Autophagy in Human Embryonic Stem Cell-Derived Cardiomyocytes, Stem Cells, 2018, 36(4): 501-513.

(5)Jun Lu; Yee-Ki Lee; Xinru Ran; Wing-Hon Lai; Ronald A. Li; Wendy Keung; Kennis Tse; Hung-Fat Tse; Xiaoqiang Yao; An abnormal TRPV4-related cytosolic Ca(2+ ) rise in response to uniaxial stretch in induced pluripotent stem cells-derived cardiomyocytes from dilated cardiomyopathy patients, Biochimica et Biophysica Acta: International Journal of Biochemistry and Biophysics, 2017, 1863(11): 2964-2972.

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