肖娟娟，博士，副研究员，欧洲杯压住平台附属医院肿瘤研究所副主任。2016年获华中科技大学生物化学与分子生物学专业博士学位，2016-2019年在华中科技大学从事肿瘤学博士后研究。主要研究方向为新癌激酶信号转导及中药单体转化应用研究。主持国家自然科学基金项目2项，省部级基金 2 项，参与并完成多项国家级、省厅级科研课题。以第一作者或通讯作者身份发表论文10余篇。

【肖娟娟代表性研究成果】

(1) Ming-Yang Li, Lin-Ni Fan, Dong-Hui Han, Zhou Yu, Jing Ma, Yi-Xiong Liu, Pei-Feng Li, Dan-Hui Zhao, Jia Chai, Lei Jiang, Shi-Liang Li, Juan-Juan Xiao, Qiu-Hong Duan, Jing Ye, Mei Shi, Yong-Zhan Nie, Kai-Chun Wu, Dezhong Joshua Liao, Yu Shi, Yan Wang, Qing-Guo Yan, Shuang-Ping Guo, Xiu-Wu Bian, Feng Zhu,* Jian Zhang*, Zhe Wang*; Ribosomal S6 protein kinase 4 promotes radioresistance in esophageal squamous cell carcinoma, Journal of Clinical Investigation, 2020, 130(8): 4301-4319. (期刊论文)

(2) Qin Tian, Ping Yuan, Chuntao Quan, Mingyang Li, Juanjuan Xiao, Lu Zhang, Hui Lu, Tengfei Ma, Ling Zou, Fei Wang, Peipei Xue, Xiaofang Ni, Wei Wang, Lin Liu, Zhe Wang*, Feng Zhu*, Qiuhong Duan*; Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis ofcolorectal cancer, Oncogene, 2020, 39(20): 3980-3996. (期刊论文)

(3) Xiao, Juanjuan#; Wang, Fei#; Lu, Hui; Xu, Sanpeng; Zou, Ling; Tian, Qin;Fu, Yang; Lin, Xuan; Liu, Lin; Yuan, Ping; Ni, Xiaofang; Ma, Tengfei; Zeng,Fanfan; Xue, Peipei; Xiu, Ruijuan; Zhang, Jianmin; Ji, Xinying; Hu, Hongbo; Lu,Shangyun; Dai, Hongtian; Li, Yuan; Chu, Qian*; Zhao, Xia*; Duan, Qiuhong*; Zhu,Feng*; Targeting the COX2/MET/TOPK signaling axis induces apoptosis in gefitinib-resistant NSCLC cells , Cell Death & Disease, 2019, 10: 0-777.(期刊论文)

(4) Juanjuan Xiao#, Lu Zhang#, Huijun Yi, Ling Zou, Jianmei Mo, Feng Xue, Jinhua Zheng, Yingze Huang, Hui Lu, Hansheng Wu, Peipei Xue, Xin Zhang, Lifei He, Zhaoxin Li, Shigui Pang, Guibin Qiao*, Qiuhong Duan*, Feng Zhu*; Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC, Cell Death and Disease, 2022, 13(9):828. (期刊论文)

 (5) Juanjuan Xiao*†, Hui Lu*†, Tengfei Ma†, Xiaofang Ni†, Teding Chang, Man Liu, Nijie Li, Peijiang Lu, Changshu Ke, Qin Tian, Ling Zou, Fei Wang, Wei Wang, Lu Zhang, Ping Yuan, Lin Liu, Jianmin Zhang, Fei Shi, Qiuhong Duan* and Feng Zhu*. Worenine Prevents Solar Ultraviolet–Induced Sunburn by Inhibiting JNK2. Front Pharmacol. 2022 ;13:881042.(期刊论文)

 (6)Lu Zhang; Fei Wang; Huijun Yi; Svetlana P Ermakova; Olesya S Malyarenko; Jianmei Mo; Yingze Huang; Qiuhong Duan*; Juanjuan Xiao*; Feng Zhu*. The role of T-LAK cell-originated protein kinase in targeted cancer therapy, Mol Cell Biochem, 2022;477(3):759-769. (期刊论文)

(7)Jingyu Yang, Heng Niu, ShiGui Pang, Mignlong Liu, Feng Chen, Zhaoxin Li, Lifei He, Jianmei Mo, Huijun Yi, Juanjuan Xiao, Yingze Huang*. MARK3 kinase: Regulation and physiologic roles, Cellular Signalling, 2023;103:110578. (期刊论文)